Benzylation of Imines with Activated Boronate Nucleophiles
نویسندگان
چکیده
منابع مشابه
3-Bromooxindoles as nucleophiles in asymmetric organocatalytic Mannich reactions with N-Ts-imines.
A direct asymmetric Mannich reaction of N-unprotected 3-bromooxindoles with N-Ts-imines catalyzed by bifunctional thiourea derived from 2-substituted cinchona alkaloid was developed. Products with vicinal chiral tertiary and brominated quaternary stereogenic centers were achieved in excellent diastereo- and enantioselectivity (up to 99 : 1 dr, 99% ee).
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ژورنال
عنوان ژورنال: European Journal of Organic Chemistry
سال: 2019
ISSN: 1434-193X
DOI: 10.1002/ejoc.201801804